| Round |
DraftPick |
Team |
Pick/Player |
Salary |
Status |
| 1 | 1 | New York Mets | WRIGHT, DAVID (3B) [Protected] | 7750000 | Signed |
| 1 | 2 | Houston Astros | MAUER, JOE (C) [Protected] | 10500000 | Signed |
| 1 | 3 | Cleveland Indians | UPTON, B.J. (OF) [Protected] | 435000 | Signed |
| 1 | 4 | Oakland Athletics | GREINKE, ZACK (SP) [Protected] | 3750000 | Signed |
| 1 | 5 | | 2008 ROUND 6-18, DRAFTED (3B) [Unprotected] | 400000 | Waivers |
| 1 | 6 | Baltimore Orioles | RIOS, ALEXIS (OF) [Protected] | 6400000 | Signed |
| 1 | 7 | New York Mets | SIZEMORE, GRADY (OF) [Protected] | 4766666 | Signed |
| 1 | 8 | Pittsburgh Pirates | KOTCHMAN, CASEY (1B) [Protected] | 2885000 | Signed |
| 1 | 9 | Anaheim Angels | KAZMIR, SCOTT (SP) [Protected] | 6000000 | Signed |
| 1 | 10 | Chicago Cubs | SWISHER, NICK (OF) [Protected] | 5400000 | Signed |
| 1 | 11 | | CAPELLAN, JOSE (RP) [Unprotected] | 400000 | Free agent |
| 1 | 12 | New York Mets | CLOSSER, J.D. (C) [Unprotected] | 400000 | Signed |
| 1 | 13 | | 2007 ROUND 3-29, DRAFTED (SP) [Unprotected] | 400000 | Waivers |
| 1 | 14 | Pittsburgh Pirates | REED, JEREMY (OF) [Unprotected] | 925000 | Signed |
| 1 | 15 | Kansas City Royals | SLEDGE, TERRMEL (OF) [Unprotected] | 400000 | Signed |
| 1 | 16 | New York Yankees | MATSUI, KAZUO (2B) [Protected] | 5500000 | Signed |
| 1 | 17 | Florida Marlins | FRANCIS, JEFF (SP) [Protected] | 3750000 | Signed |
| 1 | 18 | | CASTILLO, JOSE (3B) [Unprotected] | 400000 | Free agent |
| 1 | 19 | San Diego Padres | HOLLIDAY, MATT (OF) [Protected] | 13500000 | Signed |